The Difference in Obesity Between Adults and Elderly with Knee Osteoarthritis
DOI:
https://doi.org/10.21776/ub.crjim.2023.004.02.02Keywords:
Knee Osteoarthritis, OsteoarthritisAbstract
Background: Knee osteoarthritis (KOA) is one of the most common diseases of arthritis. The increase in KOA prevalence is also affected by the increase in obesity prevalence as one of the KOA risk factors.
Aim: To see the difference in obesity association with KOA between adults and the elderly.
Methods: The study design is analytic cross-sectional. 102 cases and controls data each are collected from Tarempa public health center (Phc) medical records by simple random sampling using a random number generator. Data taken is the latest patient visit record in the form of name, age, gender, weight, and height. Data are then analyzed using SPSS. This study's ethical clearance is accepted by the ethic committee faculty of medicine University of Sumatera Utara.
Results: 59 (28.9%) men and 83 (71.1%) women participated in this study. The mean age of KOA subjects is 57.5 ± 11,4 with the most age range being 50-59 years old (38.2%). 71 (69.6%) KOA subjects are obese. The results of data analysis show that people ≥ 50 y.o with obesity were at 2.7 times more risk of suffering KOA than the normoweight or overweight people. There is no association between obesity and KOA in people under 50 years old.
Conclusion: The risk of obesity developing into knee OA increased with age
References
Park J, Mendy A, Vieira ER. Various Types of Arthritis in the United States: Prevalence and Age-Related Trends From 1999 to 2014. Am J Public Health. 2018 Feb 1;108(2):256–8.
Sun X, Zhen X, Hu X, Li Y, Gu S, Gu Y, et al. Osteoarthritis in the middle-aged and elderly in china: Prevalence and influencing factors. Int J Environ Res Public Health. 2019 Dec 1;16(23).
Magnusson K, Turkiewicz A, Englund M. Nature vs nurture in knee osteoarthritis – the importance of age, sex and body mass index. Osteoarthritis Cartilage. 2019 Apr 1;27(4):586–92.
Misra D, Fielding RA, Felson DT, Niu J, Brown C, Nevitt M, et al. Risk of Knee Osteoarthritis With Obesity, Sarcopenic Obesity, and Sarcopenia. Arthritis and Rheumatology. 2019 Feb 1;71(2):232–7.
Chen L, Zheng JJY, Li G, Yuan J, Ebert JR, Li H, et al. Pathogenesis and clinical management of obesity-related knee osteoarthritis: Impact of mechanical loading. Vol. 24, Journal of Orthopaedic Translation. Elsevier (Singapore) Pte Ltd; 2020. p. 66–75.
Godziuk K, Prado CM, Woodhouse LJ, Forhan M. Prevalence of sarcopenic obesity in adults with end-stage knee osteoarthritis. Osteoarthritis Cartilage. 2019 Dec 1;27(12):1735–45.
Khan B, Khan O, Zehra S, Pharm Sci PJ, Yusuf Khan O, Azhar A, et al. Association between obesity and risk of knee osteoarthritis Association between Genetic Polymorphism of Antioxidant Enzyme Genes and Risk of Cataract in Type 2 Diabetic Patients View project Cell cycle and tumor growth regulators in breast carcinoma of Pakistan View project Association between obesity and risk of knee osteoarthritis. Article in Pakistan Journal of Pharmaceutical Sciences [Internet]. 2020;33(1):295–8. Available from: https://www.researchgate.net/publication/339439961
Lee S, Kim SJ. Prevalence of knee osteoarthritis, risk factors, and quality of life: The Fifth Korean National Health And Nutrition Examination Survey. 2015.
Sasaki E, Ota S, Chiba D, Kimura Y, Sasaki S, Yamamoto Y, et al. Early knee osteoarthritis prevalence is highest among middle-aged adult females with obesity based on new set of diagnostic criteria from a large sample cohort study in the Japanese general population. Knee Surgery, Sports Traumatology, Arthroscopy. 2020 Mar 1;28(3):984–94.
Bañuls-Mirete M, Lombardi AF, Posis AIB, Shadyab AH, Chang EY, Lane NE, et al. Effusion-synovitis worsening mediates the association between body mass index and Kellgren-Lawrence progression in obese individuals: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2022 Sep 1;30(9):1278–86.
Culvenor AG, Øiestad BE, Hart HF, Stefanik JJ, Guermazi A, Crossley KM. Prevalence of knee osteoarthritis features on magnetic resonance imaging in asymptomatic uninjured adults: a systematic review and meta-analysis. Br J Sports Med. 2019 Oct 1;53(20):1268–78.
Landsmeer MLA, de Vos BC, van der Plas P, van Middelkoop M, Vroegindeweij D, Bindels PJE, et al. Effect of weight change on progression of knee OA structural features assessed by MRI in overweight and obese women. Osteoarthritis Cartilage. 2018 Dec 1;26(12):1666–74.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Clinical and Research Journal in Internal Medicine

This work is licensed under a Creative Commons Attribution 4.0 International License.
The copyright of the received article shall be assigned to the journal as the publisher of the journal. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.